Semaglutide is

• A GLP-1 receptor agonist (single pathway)
• Developed by Novo Nordisk
• Works by:
  • reducing appetite
  • slowing gastric emptying
  • improving insulin response

Cycle length

Same principle again:

Semaglutide is NOT meant to be cycled

How it’s actually used:

• Designed for continuous, long-term use
• Clinical trials:
  • Typically 68 weeks+
  • Effects build gradually over months

Semaglutide 10 (10 mg/3ml/300units) 30 units = 1mg

Weeks 1–4: 7 units weekly

Weeks 5–8: 15 units weekly

Semaglutide 20 (20mg/3ml/300units) 15 units =1mg

Weeks 9–12: 30 units weekly (This does is not for first time use)

Weeks 13–16: 45 units weekly

Weeks 17 Onwards: 60-75 units weekly (Repeat cycle until research is complete)

Cagrilintide is

is an amylin analogue developed by Novo Nordisk.

• Mimics the hormone amylin (co-secreted with insulin)
• Works differently from GLP-1 drugs:
  • increases satiety (you feel full faster)
  • slows gastric emptying
  • reduces food intake

It’s often studied in combination with semaglutide (called “CagriSema”), which targets multiple appetite pathways.

Cycle length (research / real-world use)

Same key principle as the others:

👉 Cagrilintide is NOT a cycle-based compound

In studies:

• Used as continuous therapy
• Trials typically run:
  • 20–68 weeks+
  • Effects build gradually over time

Cagrilintide 10 (10 mg/3ml/300units) 30 units = 1mg

Weeks 1–4: 30 units weekly

Weeks 5–8: 45 units weekly (Repeat cycle until research is complete)

Tissue Repair & Longevity

GHK-Cu (short for glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper-binding peptide found in human plasma, saliva, and urine. It’s very different from the weight-loss drugs you’ve been asking about.

What GHK-Cu is

• A tripeptide + copper ion
• Known for roles in:
  • skin regeneration
  • wound healing
  • collagen production
  • Widely used in cosmetics and dermatology research

What it’s studied for

Research suggests GHK-Cu may:

• Stimulate collagen and elastin
• Improve skin elasticity and wrinkles
• Promote hair growth (early-stage evidence)
• Support wound healing and tissue repair
• Have anti-inflammatory and antioxidant effects

Possible Cycle:

• 12 weeks followed by 1-2 months off, or month on month off

GHK-Cu 50 (50 mg/3ml/300units) 6 units = 1mg:

• 6–12 units nightly

TB-500 is

• A synthetic peptide fragment designed to mimic Tβ4 activity
• Involved in:
  • cell migration
  • angiogenesis (new blood vessel formation)
  • tissue repair signaling

What it’s studied for

Research areas include:

• muscle and tendon healing
• ligament recovery
• wound healing
• inflammation reduction
• possible cardiac repair effects

Cycle length” (research / anecdotal use)

1. “Loading phase”

• ~2–6 weeks
• Higher frequency dosing

1. “Maintenance phase”

• Additional weeks or intermittent use

Typical total duration discussed:

• 4–12 weeks

TB500 10 (10 mg/3ml/300units) 30 units = 1mg:

• 10 units nightly or 30 units 2–3x weekly

BPC-157 is

• A synthetic fragment derived from a protein found in human gastric juice
• Not an approved medication
• Studied mainly in animal models

It’s often categorized as a gut-derived healing peptide

What it’s studied for

Research suggests potential effects on:

• tendon and ligament healing
• muscle repair
• gut lining protection (ulcers, inflammation)
• nerve healing
• angiogenesis (blood vessel formation)

One unique angle:

• Strong focus on gut repair + systemic healing signaling

Cycle length” (research / anecdotal use)

Like TB-500:

Common informal/research-style use patterns:

• Duration often discussed:
  • 2–6 weeks (short protocols)
  • sometimes extended to 8–12 weeks
  • Used either:
  • continuously during that period
  • or until an injury “resolves”

BPC-157 10 (10 mg/3ml/300units) 30 units = 1mg:

• 10 units nightly

Wolverine blend is

• A dual peptide formulation:
  • BPC-157 → gut-derived, tendon/ligament + localized repair
  • TB-500 → systemic repair, cell migration, angiogenesis

The nickname comes from the Wolverine character because of his rapid healing ability.

Why they’re combined

The idea is “synergy”:

• BPC-157:
  • targets connective tissue + gut + inflammation
  • TB-500:
  • enhances systemic healing + cell movement + blood flow

Together they:

• hit multiple repair pathways at once
• may improve:
  • muscle recovery
  • tendon/ligament healing
  • inflammation control

Cycle length

Like the individual peptides:

What’s commonly discussed (non-clinical):

• Typical duration:
  • 4–8 weeks
  • sometimes 6–12 weeks depending on injury severity
  • Often structured as:
  • continuous use during that period
  • then stop or reassess

Wolverine Blend 20 (10mg BPC 157& 10mg Tb 500) (20 mg/3ml/300units) 15 units = 1mg

• 6–12 units nightly

Glow Blend is

The Glow blend isn’t one official drug—it’s a combo peptide mix, almost always made of:

• GHK-Cu → skin regeneration / collagen
• BPC-157 → tissue repair + anti-inflammatory
• TB-500 → systemic healing + cell migration

Most commonly:

• ~50 mg GHK-Cu + 10 mg BPC-157 + 10 mg TB-500

What it’s designed for (research context)

This blend is basically trying to stack three mechanisms at once:

• Skin + cosmetic side (GHK-Cu)
  • collagen, elasticity, “glow”
  • Localized repair (BPC-157)
  • tendons, ligaments, gut
  • Systemic repair (TB-500)
  • blood flow, cell migration, recovery

In research, it’s explored for:

• tissue regeneration
• wound healing
• inflammation modulation
• skin biology / anti-aging pathways

Cycle length

What’s commonly discussed (non-medical / anecdotal):

• 4–8 weeks most typical
• sometimes up to 12 weeks

From community discussion:

“cycle 4–5 weeks” (example anecdotal protocol)

The “cycle” is completely informal, not based on human trials.

Glow 70 (10mg BPC 157, 50mg GHKCU & 10mg TB500) (70 mg/3ml/300units) 4.28 units = 1 mg

• 8–12 units nightly

Klow Blend” is

The Klow blend is just a variation of the Glow stack with one extra peptide added:

• GHK-Cu → skin / collagen / regeneration
• BPC-157 → localized tissue repair
• TB-500 → systemic healing
• KPV → anti-inflammatory peptide

What KPV adds

KPV (Lys-Pro-Val) is a small peptide fragment derived from alpha-MSH

It’s mainly studied for:

• strong anti-inflammatory effects
• immune modulation
• gut inflammation (IBD-type models)
• skin inflammation (acne, dermatitis models)

Adding KPV turns Glow into something more inflammation-focused:

• Glow blend:
  • regeneration + skin + healing
  • Klow blend:
  • regeneration + skin + healing + inflammation control

The theoretical benefit:

• better for:
  • irritated skin
  • chronic inflammation
  • gut + skin crossover issues

Cycle length

Common anecdotal ranges:

• 4–8 weeks typical
• sometimes up to 10–12 weeks

KLOW 80 (10mg BPC 157, 50mg GHKCU, KPV 10mg & 10mg TB500) (80 mg/3ml/300units)

3.75 units = 1mg

• 8–12 units nightly

Performance & Metabolic Regulation

MOTS-c

is a mitochondrial-derived peptide—meaning it’s encoded by mitochondrial DNA rather than nuclear DNA.

• Full name: mitochondrial open reading frame of the 12S rRNA-c
• Discovered relatively recently in metabolic research
• Plays a role in cellular energy regulation

MOTS-c is mainly researched in the context of metabolism and aging.

Potential effects (mostly animal + early human data):

• Improved insulin sensitivity
• Enhanced glucose metabolism
• Increased fat utilization
• Support for exercise performance
• Possible anti-aging / longevity pathways

Mechanistically, it’s linked to:

• activation of AMP-activated protein kinase (AMPK)
• regulation of metabolic stress responses

What makes it interesting

Unlike GLP-1 drugs (semaglutide, tirzepatide):

• Doesn’t suppress appetite directly
• Works more on how your body uses energy

Think:

• GLP-1s → “eat less”
• MOTS-c → “use energy better”

Cycle length

• 2–4 weeks short protocols
• sometimes 4–8 weeks
• Often used:
  • daily or several times per week
  • sometimes around training periods

MOTS-C 30 (30 mg/3ml/300units) 10 units = 1mg

• 10 units daily or 30–35 units 2x weekly (morning fasted)

CJC-1295 (no DAC) + Ipamorelin is

This is a paired peptide protocol used in research contexts to stimulate natural growth hormone (GH) release.

Components:

• CJC-1295 (no DAC)
  • A modified version of **growth hormone-releasing hormone
  • Signals the pituitary to release GH
  • Ipamorelin
  • A ghrelin mimetic (growth hormone secretagogue)
  • Triggers GH release without strongly increasing cortisol or prolactin

Together:

They synergistically increase pulsatile GH release

Why they’re combined

Each peptide hits a different pathway:

• CJC-1295 → increases baseline GH signaling
• Ipamorelin → triggers GH pulses

Result:

• more natural GH rhythm vs using either alone
• often described as:
  • smoother
  • more physiological

Cycle length

But this combo is one of the more “structured” ones in peptide discussions.

Common informal protocols:

• 8–12 weeks typical
• sometimes extended to:
  • 12–16 weeks
  • Often followed by:
  • a break (e.g. 4 weeks)

CJC-1295 no dac + Ipamorelin 20 (10mg Cjc-1295 & 10mg Ipamorelin) (20 mg/3ml/300units) 15 units = 1mg

• 6–12 units nightly

Ipamorelin

is a growth hormone secretagogue—a peptide that stimulates your body to release its own growth hormone (GH).

• It mimics the action of ghrelin
• Acts on the growth hormone secretagogue receptor (GHSR)
• Considered one of the “cleaner” GH-releasing peptides

Key point:

It triggers natural GH pulses rather than replacing GH directly

Ipamorelin is studied for:

• increased growth hormone (GH) and IGF-1
• improved recovery and repair
• better sleep quality
• potential fat loss (indirect)
• mild support for lean mass

Effects are generally:

• subtle
• gradual
• dependent on consistency

Cycle length

Common informal / research-style use:

• 8–12 weeks typical
• sometimes extended to:
  • 12–16 weeks
  • Often followed by:
  • a break period (e.g. a few weeks)

Ipamorelin 20 (20 mg/3ml/300units) 15 units = 1mg

• 6–12 units nightly

5-Amino-1MQ

(5-amino-1-methylquinolinium) is an experimental small molecule, not a peptide, that’s being studied for fat loss and metabolic regulation.

• It works by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT)
• NNMT plays a role in:
  • fat storage
  • energy metabolism
  • cellular methylation balance

It’s designed to shift the body toward burning fat rather than storing it

Potential effects:

• reduced fat accumulation
• increased metabolic rate
• improved insulin sensitivity
• changes in energy utilization

It’s often positioned as:

• a “metabolic enhancer”
• not an appetite suppressant (unlike GLP-1 drugs)

How it’s different from GLP-1 drugs

Compound Main mechanism

Semaglutide Appetite suppression

Tirzepatide Appetite + insulin

MOTS-c Cellular energy regulation

5-Amino-1MQ Fat metabolism via NNMT inhibition

• GLP-1 → eat less
• 5-Amino-1MQ → burn differently

Cycle length

4–8 weeks typical

• sometimes extended to 8–12 weeks

5-Amino-1MQ 50 (50 mg/3ml/300units) 6 units = 1mg

• 10-20 units- morning fasted

Immunity & Longevity

Epithalon

Is (also called Epitalon or Epithalone) is a synthetic peptide derived from a natural peptide called Epithalamin, which comes from the pineal gland.

• Short peptide: 4 amino acids
• Developed in Russia for aging and longevity research
• Often grouped with “anti-aging peptides”

Potential effects studied:

• activation of telomerase
• possible telomere length support
• improved sleep regulation (via melatonin pathways)
• antioxidant effects
• potential lifespan extension (in animals)

Big claim:

It may influence biological aging processes

How it works (simplified)

Epithalon is thought to:

• act on the pineal gland
• influence melatonin production
• regulate genes linked to aging and cell cycles

Cycle length

• 10–20 days per cycle some extend to 30 days.
• repeated:
  • 1–2 times per yea

Why people use it

• anti-aging / longevity
• improved sleep quality
• circadian rhythm support
• general “recovery” feeling

• Epithalon 50 (50 mg/3ml/300units) 6 units= 1mg
• 10-20 units nightly

Thymosin Alpha-1

is a naturally occurring peptide derived from the thymus gland.

• It’s a fragment of prothymosin alpha
• Plays a role in immune system regulation
• Unlike many peptides you’ve asked about, this one actually has clinical use in some countries

What it’s used for (medical + research)

TA-1 has been studied and used for:

• immune system support
• chronic viral infections (e.g. hepatitis B/C)
• adjunct therapy in cancer treatment
• immune recovery in weakened states

It works by:

• enhancing T-cell function
• improving immune signalling and response

How it works (simplified)

Thymosin Alpha-1 helps:

• activate immune cells (especially T lymphocytes)
• regulate cytokines (immune signalling molecules)
• improve the body’s ability to respond to infections

Cycle length

This one is different because it does have real clinical protocols.

In medical use:

• Often used for:
  • several weeks to months
  • Example patterns:
  • 6–12 weeks common
  • sometimes longer depending on condition

Thymosin Alpha-1 20 (20 mg/3ml/300units) 15 units = 1mg

• 30 units 3 x week

Hormonal Compounds

Testosterone cypionate

is a long-acting ester of testosterone used in testosterone replacement therapy (TRT).

• It’s a form of testosterone
• Designed for slow release after injection
• Commonly prescribed for clinically low testosterone (hypogonadism)

What TRT with testosterone cypionate does

TRT aims to restore testosterone to a normal physiological range.

Potential benefits:

• improved energy
• increased libido
• better mood
• improved muscle mass and strength
• increased bone density

Cycle length

TRT is NOT a cycle

This is the biggest difference from everything else you’ve asked about.

• ❌ Not 8–12 weeks
• ❌ Not on/off
• ✅ Long-term (often lifelong) therapy

TRT = continuous hormone replacement, not cycling

Stopping TRT:

• testosterone levels drop back to baseline (often low again)
• symptoms return

📊 Typical TRT dosing (medical context)

• Usually:
  • 100–200 mg per week
  • Injection frequency: micro dosed daily or every other day

TRT typically shuts down natural testosterone production

Fertility note

• TRT can significantly reduce sperm production
• Sometimes managed with:
  • human chorionic gonadotropin (hCG)

TRT vs “cycling steroids”

TRT Steroid cycle

Medical Performance use

Stable hormone levels Supraphysiological levels

Long-term Short-term

Health-focused Performance-focused

TRT = replacement, not enhancement

TRT Testosterone Cypionate 750(750 mg/3ml/300units) 0.4 units = 1mg

• 6-9 units daily or 12-18 units alternate days

NAD⁺

Is (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body and is essential for energy production and cellular health.

• Central to cellular respiration
• Required for:
  • converting food into energy (ATP)
  • DNA repair
  • cell signaling

NAD⁺ = fuel system regulator for your cells

What it’s studied for

NAD⁺ has become popular in aging and metabolic research.

Potential roles:

• improved mitochondrial function
• enhanced energy levels
• support for brain function
• DNA repair and longevity pathways
• possible benefits in addiction recovery (studied clinically in some settings)

It interacts with:

• sirtuins (linked to aging and metabolism)

Why NAD⁺ declines

Levels naturally decrease with:

• aging
• stress
• poor metabolic health

Lower NAD⁺ is associated with:

• fatigue
• reduced metabolic efficiency
• impaired cellular repair

Cycle length

NAD⁺ isn’t really a “cycle compound” in the traditional sense

Different forms:

1. IV / injectable NAD⁺

• Often used in:
  • short protocols
  • multiple infusions

1. Oral precursors (more common)

• nicotinamide riboside
• nicotinamide mononucleotide

These are typically:

• taken daily, long-term
• not cycled

Expected effects

• mild increase in energy
• improved recovery feeling
• subtle cognitive benefits

Important:

• effects are usually subtle, not dramatic
• NAD⁺ itself is biologically natural
• Precursors (NR, NMN) are generally well tolerated

But:

• long-term high-dose effects still being studied
• IV NAD⁺ clinics vary widely in quality

NAD 1000 (1000 mg/3ml/300units) 0.3 units = 1mg

• 10–15 units daily or 15–30 units alternate days

HGH

Is (Human Growth Hormone) is a naturally occurring hormone produced by the pituitary gland.

• Scientific name: growth hormone
• It regulates:
  • growth
  • metabolism
  • tissue repair
  • body composition

Medical version:

• Somatropin (bioidentical HGH)

What HGH does in the body

HGH works both directly and through another hormone:

• stimulates liver to produce insulin-like growth factor 1 (IGF-1)
• IGF-1 drives many of the anabolic and recovery effects

Effects:

• increased protein synthesis
• fat metabolism (lipolysis)
• tissue repair and regeneration
• improved bone density

HGH is prescribed for:

• growth hormone deficiency
• certain genetic conditions
• muscle wasting diseases

In these cases:

• it’s used as long-term therapy, similar to TRT

Cycle length

Medically:

• ❌ not cycled
• ✅ continuous, long-term use

Performance / non-medical use:

People often talk about “cycles,” but:

• common informal durations:
  • 3–6 months minimum
  • often 6–12+ months

Why longer?

• HGH works slowly
• effects take months, not weeks

HGH 100iu (100iu/3ml/300units) 3 units = 1iu

• 9–18 units daily

hCG

Is (human chorionic gonadotropin) is a hormone that mimics luteinizing hormone (LH) in the body.

• Naturally produced during pregnancy
• In men, it stimulates the testes to produce:
  • testosterone
  • sperm

Think of it as:

a signal to “turn the testes back on”

What hCG is used for

Medical uses:

• male hypogonadism
• fertility treatment
• delayed puberty

Common non-medical contexts:

• alongside TRT
• post-cycle therapy (PCT)

Why it’s used with TRT

When someone uses TRT (like testosterone cypionate):

• natural LH production shuts down
• testes stop producing testosterone
• can lead to:
  • testicular shrinkage
  • reduced fertility

hCG helps:

• maintain testicular function
• preserve fertility (partially)
• keep some natural testosterone production active

Cycle length (depends on use)

1. With TRT (ongoing use)

Not really cycled

• used continuously alongside TRT
• long-term protocol

1. Post-cycle therapy (PCT)

Short-term use

• typically 2–4 weeks
• used to restart natural production before

HCG 10000IU (10000iu/3ml/300units) 3 units = 100iu

• 15 units 3 x per week

Cognitive Peptides

Semax

is a synthetic peptide nootropic derived from a fragment of adrenocorticotropic hormone (ACTH 4–10).

• Developed in Russia
• Used there clinically (e.g. stroke recovery, cognitive disorders)
• Typically administered as a nasal spray/Sub q Inj

It’s not a stimulant like caffeine—more of a neuroregulatory peptide

What Semax does

Semax affects several brain pathways:

• increases brain-derived neurotrophic factor (BDNF)
• modulates dopamine and serotonin
• supports neuroprotection

In simple terms:

It helps with focus, memory, and brain resilience

What it’s used for

Clinical / research use:

• stroke recovery
• cognitive impairment
• neuroprotection

Nootropic use (informal):

• improved focus
• mental clarity
• learning and memory
• reduced brain fog

Cycle length

No official global standard, but Semax is more structured than most peptides.

Common use patterns:

• 2–4 weeks typical
• sometimes extended to:
  • 4–6 weeks
  • followed by:
  • a break period (e.g. 1–2+ weeks)

Short cycles with breaks are commonly used

Dosing style

• Usually Sub Q Inj
• Taken:
  • Once daily

Fast-acting:

• effects can be noticed within hours to days

Effects (realistic)

• increased focus and mental energy
• improved memory recall
• smoother cognition (not jittery)
• subtle mood lift

Compared to stimulants:

• less “wired”
• more stable and clean feeling

Semax 20 (20 mg/3ml/300units) 15 units = 1mg

• 15 units daily

Selank

is a synthetic peptide developed in Russia, derived from a fragment of an immune peptide called tuftsin.

• Designed primarily as an anxiolytic (anti-anxiety) peptide
• Typically used as a nasal spray
• Often grouped with nootropic peptides like Semax

Think of it as:

a calming, stabilizing brain peptide (not a sedative)

What Selank does

Selank influences several brain systems:

• modulates gamma-aminobutyric acid (GABA)
• affects serotonin and dopamine balance
• may increase BDNF (neuroplasticity support)

In simple terms:

• reduces anxiety
• improves emotional stability
• supports cognition indirectly

What it’s used for

Clinical / research use:

• anxiety disorders
• stress-related conditions
• cognitive support

Nootropic use (informal):

• anxiety reduction without sedation
• improved focus (by lowering mental noise)
• mood stabilization
• social anxiety support

Cycle length

No universal standard, but commonly structured:

Typical use:

• 2–4 weeks
• sometimes extended to:
  • 4–6 weeks
  • followed by:
  • a break period

So:

Short cycles with breaks are standard practice

Dosing style

• Sub Q Inj
• Taken:
  • Once daily

Effects:

• can be felt within:
  • hours to days
  • builds gradually with consistent use

Effects (realistic)

• reduced anxiety (without drowsiness)
• calmer mental state
• improved focus (indirectly)
• better stress tolerance

Compared to medications:

• not as strong as prescription anxiolytics
• but fewer side effects and no sedation

Selank vs Semax (key difference)

Peptide Effect

Semax Stimulating / focus

Selank Calming / anti-anxiety

Combined use:

• balances focus + calm
• common in “Know blends”

Selank 20 (20 mg/3ml/300units) 15 units = 1m

• 15 units daily

Melanocortin Peptides

Melanotan II (MT-2)

is a synthetic peptide analogue of alpha-MSH.

• Designed to stimulate melanin production
• Also affects other receptors in the body (not just skin)
• This is why it has more side effects than Melanotan I

In simple terms:

It’s a potent tanning peptide with systemic effects

What it does

Primary effect:

• increases skin pigmentation (tanning)

Secondary effects (due to broader receptor activity):

• increased libido
• spontaneous erections (in men)
• appetite suppression (mild)

Cycle length

Common informal structure:

1. Loading phase

• ~7–14 days
• frequent dosing
• goal: build baseline pigmentation

1. Maintenance phase

• lower frequency dosing
• used to maintain tan

Total duration:

• usually 4–8 weeks
• sometimes longer depending on goals

How fast it works

• initial effects:
  • within a few days (flushing, nausea)
  • visible tanning:
  • 1–3 weeks
  • requires:
  • some UV exposure for full effect

It enhances tanning, not replaces sunlight completely

Expected results

• deeper, faster tan

MT-2 20 (20 mg/3ml/300units) 15 units = 1mg

• Days 1–10 = 5 units daily
• 10 units 2-3 times per week

Research Disclaimer

All information contained in this guide is presented for theoretical research and development purposes only. These compounds are not approved medicines and are not intended for human consumption, diagnosis, treatment or prevention of disease.